Protandim FAQs


What is Nrf2?
Nrf2 is a protein that binds itself to a DNA sequence. It has been called the "master regulator of the body's aging process." When activated, Nrf2 enters the nucleus of a cell and stimulates protective genes and enzymes to neutralize the effects of free radicals and other reactive substances.


How is Protandim different from other antioxidant supplements?

Protandim is different from other antioxidant supplements because it is among the very first of the products that are appearing and will appear as Nrf2 activators. As far as we know, Protandim is the first potent, commercially available Nrf2 activator.

Nrf2 is a protein messenger contained in every cell of the body that sends information to the cell's DNA. When Nrf2 is activated, it enters the nucleus and turns on several hundred of these 25,000 genes, collectively known as survival genes. Protandim, as a Nrf2 activator, activates survival genes, such as antioxidant genes that keep us safe from free radicals and oxidants.

Protandim is different from other antioxidant supplements in the way it works. Instead of providing the body with additional dietary antioxidants (regular supplements fall into this category and are commonly called consumable or "direct" antioxidants), Protandim works from within your body, signaling it to boost its own production of numerous antioxidant enzymes (including the well-known ones--SOD and catalase) that already exist at the cellular level to help fight free radicals and cellular aging. This is why Protandim is significantly more effective than any other antioxidant on the market today; your body is actually producing the antioxidant power. But Protandim goes far beyond antioxidant protection; it activates hundreds of "survival genes" that help your body survive many kinds of stress.


What are the main ingredients found in Protandim?

Milk thistle extract containing 80% silymarin, bacopa extract containing 45% bacosides, ashwagandha root powder, green tea extract containing 98% polyphenols, tumeric extract containing 95% curcumin.


Are the ingredients used in Protandim "organic"?

No, they are not "certified" organic; however, they are all harvested in their natural environment.


Can I take these ingredients individually and achieve the same effect?
No, the blend of ingredients and their special formulation is unique to Protandim and holds patents. The combination of ingredients creates a synergy that has been studied and proven to provide much more antioxidant power than any food or conventional supplements. This scientific peer-reviewed study was published in the journal "Free Radical Biology and Medicine" and it also clearly shows Protandim produces a 300 percent increase in glutathione, which is a key antioxidant and anti-aging factor.


Are there any side-effects to taking Protandim?

We do not expect there to be any side effects for the typical Protandim consumer. However, some individuals have natural allergic responses to one or another of the ingredients, just as some people are allergic to pine pollen or penicillin. These allergic responses to Protandim generally appear as gastrointestinal disturbances (i.e., stomach ache, diarrhea, vomiting) or sometimes as a headache or rash on the hands or feet. The symptoms disappear if Protandim is discontinued. If you are experiencing any adverse reaction, discontinue use.


Are there situations when Protandim is not recommended?

You should consult your physician before taking Protandim when dealing with autoimmune diseases or when taking immunosuppressive drugs following a transplanted organ received from another person. Why? Because the immune system is what helps fight off viruses, bacteria and other foreign objects. When you have just received an organ from another person this could be detected as a foreign object by your immune system which will reject and try to kill it, as it would an invading microorganism. In such circumstances, your physician may maintain your immune system in a suppressed state to help avoid rejection.


Does Protandim interfere with any prescription drugs?

Just like prescription drugs, the ingredients in many supplements are metabolized in the liver and excreted by the kidneys in the urine. The ingredients in Protandim, however, are primarily metabolized and excreted by the liver into the bile. This difference decreases the likelihood of Protandim interacting with other over-the-counter products or with prescription drugs.


Can a woman who is pregnant or breastfeeding take Protandim?

Many obstetricians recommend that women stop taking everything except what they prescribe (see the warning label of the Protandim bottle). However, if your obstetrician approves Protandim, there is no known reason for concern.


Why is the T-BARS assay used to determine levels of oxidative stress?
There are many ways in which oxidative stress can be measured in the laboratory. TBARS was chosen because it has been the most widely used, with more than 8,000 published studies. These studies provide a valuable basis for comparison. TBARS reflect oxidative damage to polyunsaturated lipids, perhaps the most sensitive major class of biological molecules to free radical damage.


What is the difference between a Customer and Preferred Customer?
Customers place one-time orders at the Retail Price of $50. A Customer can choose to become a Preferred Customer and receive 20% off their product purchases, by signing up for monthly Autoships. The monthly Autoship price is $40.



Protandim and other LifeVantage products are not intended to treat, cure, prevent or mitigate any diseases. Statements made on this web site have not been evaluated by the Food and Drug Administration and should not be used to treat any diseases.